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Advancing medicine with Patient-on-a-Chip

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Innovating with Organ-on-a-Chip technology.

It is well known that patients responds very uniquely to various drugs and chemicals. For instance, a drug may be effective for a patient while it makes another one more ill. For a long time, we had no test to check the effects and response of these medicine or line of treatment individually for each patient.

Patient-on-a-Chip holds the potential to advance the field of precision medicine and provide clinicians with better information which can accurately predict patient's response to medications and treatment.  


Organ-on-a-Chip technology can be used to recapitulate true-to-life biology outside the human body. These advanced systems can create micro-environment where cells exhibit unprecedented level of biological functions and facilitates control over complex human biology and disease mechanism which arduous with other techniques. 

Scientist can harvest cells from the skin or blood of the patient. These cells can be reprogrammed into induced pluripotent stem cells which can be differentiated into any organ cell type each bearing unique genetic fingerprint of the patient.

These patient cells can be integrated with organ-on-chip devices to check the response of the treatment by exposing the cells to a single or combination of drugs. Such patient specific response can be obtained without actually administering a drug which may cause harm.

Potential of Precision Medicine.

When a patient is sick, clinician can will be able to develop a patient specific treatment to better understand the unique biology and response for the best possible outcomes. Organ-on-a-Chip technology will provide better information about how a patient respond to a specific disease condition and subsequent line of treatment. 

With the advancement of Science precision medicine will involve preventative measures as well. It's not hard to imagine the integration of clinician's expertise, data generated by devices, power of AI along with Organ-on-Chip technology. 


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